Jaundice – CAUTION ON G6PD Deficiency

Jaundice Due to G6PD Deficiency
Posted by: Dr. Sloan, MD.  :  Category: Neonatal Jaundice
 
G6PD deficiency is due to a problem with an enzyme (chemical) called G6PD found in the red blood cells of the blood. It is more common in males but females could be a carrier and remain asymptomatic- no symptoms at all. This deficiency can cause hemolytic anemia-breaking up of the RBC , usually after exposure to certain medications, foods, or even infections.Most people with G6PD deficiency don’t have any symptoms, while others develop symptoms of anemia only after RBCs have been destroyed, a condition called hemolysis. In these cases, the symptoms disappear once the cause, or trigger, is removed.  A normal life is certainly possible, if the child is aware that the condition is lifelong and must be cautious of certain medicine and chemical exposure. Keeping the list of medicine, chemical and food to be avoided is always a wise thing to do. Always present the list to the medical doctor when seeking treatment.

 
Some children with G6PD must not take asprin. Check with your specialist or paediatrician first.
 
In conclusion, patients must always be informed this is not a life threatening disease and one can live a normal life provided he is not exposed to the triggering factors. 
 
Signs of G6PD Deficiency
Posted by: Dr. Sloan, MD.  :  Category: Neonatal Jaundice
 
These are signs of glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Be alert if the child presents with the following symptoms, including jaundice, pale skin/pallor (RBCs destroyed), persistent/severe tiredness (due to low oxygen carrying capacity as a result of low RBC after being destroyed) and dark urine.

 
Ernest Beutler, M.D. (a leading expert in this field) has to say about neonatal icterus (jaundice), “Icterus neonatorum with no evidence of immunologic incompatibility occurs in some infants with G6PD deficiency. The jaundice may be quite severe and, if untreated, may result in kernicterus. Thus G6PD deficiency is a preventable cause of mental retardation, and this aspect of the disorder has considerable public health significance.”

One response to this post.

  1. Posted by muneer on September 21, 2013 at 4:17 pm

    Please send me updated record for G6PD deficiency

    Reply

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: